Organotin carboxylates: from structures to antitumour activities

Xiao Xiao, wenliang Li, Chengwu Liang, Wenxiu Zhao

Abstract


An overview is given of the research on organotin carboxylates, including architecture formation, molecular and supramolecular architectural styles, spectra studies and antitumour activities. The development of antitumour organotin carboxylates is discussed for selected classes. They show high activities but the therapeutic potential is deeply hampered by their solubility in water and side effects. Further research to develop novel antitumour organotin carboxylates and effective methods to achieve higher water solubility need to be carried out.

Keywords


Organotin carboxylate; molecular structure; supramolecular structure; antitumour activity; Tin NMR study.

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DOI: http://dx.doi.org/10.18088/ejbmr.1.4.2015.pp23-27